发明名称 |
ENGINEERING THE PRODUCTION OF A CONFORMATIONAL VARIANT OF OCCIDIOFUNGIN THAT HAS ENHANCED INHIBITORY ACTIVITY AGAINST FUNGAL SPECIES |
摘要 |
Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided. |
申请公布号 |
US2014147416(A1) |
申请公布日期 |
2014.05.29 |
申请号 |
US201314090679 |
申请日期 |
2013.11.26 |
申请人 |
THE TEXAS A&M UNIVERSITY SYSTEM |
发明人 |
SMITH JAMES LEIF;RAVICHANDRAN AKSHAYA;LU SHIEN;GU GANYU |
分类号 |
A01N37/46;A61K38/12;C07K7/54 |
主分类号 |
A01N37/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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