发明名称 Process for purification of 1-methylpyrazole-4-carboxylic acid esters
摘要 The present invention relates to improvements in processes towards the production 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid, which is a useful intermediate in fungicide production. In particular, the invention relates to a process for treating a compound of formula III, wherein R1 is C1-C6 alkyl and R2 is CF3, CF2H or CFH2, comprising the steps of a) contacting a compound of formula III with base, and b) separating the compound of formula III and the base.
申请公布号 US8735600(B2) 申请公布日期 2014.05.27
申请号 US201013320730 申请日期 2010.04.20
申请人 MCDOUGALD GRAHAM;MUXWORTHY JAMES PETER;WILDE BEVERLEY ANN;SYNGENTA LIMITED 发明人 MCDOUGALD GRAHAM;MUXWORTHY JAMES PETER;WILDE BEVERLEY ANN
分类号 C07D231/14;C07D409/12 主分类号 C07D231/14
代理机构 代理人
主权项
地址