发明名称 |
THIAZOLYL AND OXAZOLYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS |
摘要 |
Compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis or pelvic pain syndrome. |
申请公布号 |
WO2014078322(A1) |
申请公布日期 |
2014.05.22 |
申请号 |
WO2013US69728 |
申请日期 |
2013.11.12 |
申请人 |
ARRAY BIOPHARMA INC.;BRANDHUBER, BARBARA, J.;JIANG, YUTONG;KOLAKOWSKI, GABRIELLE, R.;WINSKI, SHANNON, L. |
发明人 |
BRANDHUBER, BARBARA, J.;JIANG, YUTONG;KOLAKOWSKI, GABRIELLE, R.;WINSKI, SHANNON, L. |
分类号 |
C07D263/48;C07D277/46;C07D403/12 |
主分类号 |
C07D263/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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