| 发明名称 |
OLIGONUCLEOTIDE CONJUGATES |
| 摘要 |
<p>The invention relates to the field of oligonucleotide therapeutics, and in particular to the use of a cleavable, e.g. a phosphodiester region covalently attached to a conjugate, a targeting group or blocking group to enhance the properties of the oligonucleotides, for example to improve the therapeutic index.</p> |
| 申请公布号 |
CA2889596(A1) |
申请公布日期 |
2014.05.22 |
| 申请号 |
CA20132889596 |
申请日期 |
2013.11.14 |
| 申请人 |
ROCHE INNOVATION CENTER COPENHAGEN A/S |
发明人 |
ALBAEK, NANNA;HANSEN, HENRIK;KAMMLER, SUSANNE;RAVN, JACOB;ORUM, HENRIK |
| 分类号 |
C12N15/11;C12N15/113 |
主分类号 |
C12N15/11 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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