发明名称 |
Method of producing a modified (poly) peptide |
摘要 |
This invention relates to a method of producing a modified (poly)peptide, said method comprising the step of modifying in an organic solvent a crown ether-bound (poly)peptide at one or more carboxylic groups by esterification or thioesterification and/or at the amino group of the N-terminal amino acid by amidation or alkylation. Furthermore provided are (poly)peptides and antibodies obtainable with the method of the invention as well as medical uses thereof. |
申请公布号 |
US8729228(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US20060088119 |
申请日期 |
2006.09.28 |
申请人 |
BOTTI PAOLO;UNIVERSITY OF GENEVA |
发明人 |
BOTTI PAOLO |
分类号 |
A61K38/00;C07K5/00;C07K7/00;C07K16/00;C07K17/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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