发明名称 LXR AND FXR MODULATORS
摘要 Compounds of the invention are disclosed, such as compounds of formulae LX-LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
申请公布号 EP2121621(B1) 申请公布日期 2014.05.07
申请号 EP20070865385 申请日期 2007.12.07
申请人 EXELIXIS PATENT COMPANY LLC 发明人 BOREN, BRANT CLAYTON;BUSCH, BRETT B.;GU, XIAO-HUI;JAMMALAMADAKA, VASU;LU, SHAO-PO;MARTIN, RICHARD;MOHAN, RAJU;SCHWEIGER, EDWIN;STEVENS, WILLIAM C. JR.;WANG, TIE-LIN;XIE, YINONG;XU, WEI
分类号 C07D233/90;A61K31/415;A61K31/4164;A61P3/10;C07D231/10 主分类号 C07D233/90
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