发明名称 |
Prevention and treatment of oxidative stress disorders by gluthathione and phase II detoxification enzymes |
摘要 |
The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders. |
申请公布号 |
US8709406(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US201213670161 |
申请日期 |
2012.11.06 |
申请人 |
BRASSICA FOUNDATION FOR CHEMOPROTECTION RESEARCH;BRASSICA FOUNDATION FOR CHEMOPROTECTION RESEARCH,INC. |
发明人 |
GAO XIANGQUN;DINKOVA-KOSTOVA ALBENA T.;TALALAY PAUL |
分类号 |
A61K38/44;A61K45/00;A61K31/00;A61K31/145;A61K31/26;A61K38/45;A61K38/46;A61K38/53;A61P25/28;A61P27/02;A61P43/00 |
主分类号 |
A61K38/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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