Therapeutic applications of fatty acid amide hydrolase inhibitors

摘要

Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors). Disclosed herein are potent inhibitors of FAAH for use for treating a disorder, selected from acute stress disorder and post-traumatic stress disorder.