发明名称 HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
摘要 The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
申请公布号 US2014107096(A1) 申请公布日期 2014.04.17
申请号 US201314053682 申请日期 2013.10.15
申请人 JANSSEN PHARMACEUTICA NV 发明人 LEONARD KRISTI A.;BARBAY KENT;EDWARDS JAMES P.;KREUTTER KEVIN D.;KUMMER DAVID A.;MAHAROOF UMAR;NISHIMURA RACHEL;URBANSKI MAUD;VENKATESAN HARIHARAN;WANG AIHUA;WOLIN RONALD L.;WOODS CRAIG R.;FOURIE ANNE;XUE XIAOHUA
分类号 C07D401/06;A61K31/4709;A61K45/06;C07D401/14;C07D417/14 主分类号 C07D401/06
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