Nanoparticle Plasmonic Sensor for Localized Surface Plasmon Resonance

摘要

The present invention provides a sensor for detecting the binding of molecules to membrane surfaces. The sensor comprises a nanoparticle coated with a continuous layer of silica, and having a ligand attached thereto, for detection of an analyte in a solution. The nanoparticle can be further coated with a continuous membrane, such as a lipid bilayer.