PHARMACEUTICAL COMPOSITIONS COMPRISING 15-HETRE AND METHODS OF TREATING OR PREVENTING ARTHRITIS USING SAME

摘要

The disclosure generally relates to compositions comprising fatty acids, or derivatives thereof (e.g., CI-C4 esters) including, for example, 15-HETrE for the treatment and/or prevention of arthritis. Arthritis-often divided into two categories referred to as osteoarthritis (OA) and rheumatoid arthritis (RA)-is a painful condition resulting in a lower quality of life. OA, also commonly referred to as degenerative joint disease, is characterized by an imbalance between the synthesis and degradation of articular cartilage.