PREPARATION METHOD OF AGOMELATINE SOLID PREPARATION

摘要

A preparation method of an agomelatine solid preparation comprises: mixing agomelatine or pharmaceutically acceptable salts with cross-linked polyvinylpolypyrrolidone; hot-melting the mixture to prepare particles; and then mixing the particles with other pharmaceutically acceptable carriers to be tableted or filled to form capsules. The agomelatine solid preparation prepared by the method is stable and controllable in quality and quick in dissolution.