摘要 |
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein. |
申请人 |
BESONG GILBERT EBAI;BRAIN CHRISTOPHER THOMAS;BROOKS CLINTON ALAN;CONGREVE MILES STUART;DAGOSTIN CLAUDIO;HE GUO;HOU YING;HOWARD STEVEN;LI YUE;LU YIPIN;MORTENSON PAUL NEIL;SMITH TROY D.;SUNG MOO JE;WOODHEAD STEVEN JOHN;WRONA WOJCIECH;LAGU BHARAT;NOVARTIS AG;ASTEX THERAPEUTICS, LTD. |
发明人 |
BESONG GILBERT EBAI;BRAIN CHRISTOPHER THOMAS;BROOKS CLINTON ALAN;CONGREVE MILES STUART;DAGOSTIN CLAUDIO;HE GUO;HOU YING;HOWARD STEVEN;LI YUE;LU YIPIN;MORTENSON PAUL NEIL;SMITH TROY D.;SUNG MOO JE;WOODHEAD STEVEN JOHN;WRONA WOJCIECH;LAGU BHARAT |