发明名称 Tetracyclic compounds
摘要 597477 Provided is a therapeutic and preventive agent effective against diseases accompanied by an abnormality of ALK, such as cancers, cancerous metastases, depression, or cognitive dysfunction, the agent containing an ALK-inhibitory compound. The agent comprises a medicinal composition containing a compound represented by general formula (I), wherein the variables are defined in the specification, a salt of the compound, or a solvate of either. In one embodiment the compound is 9-(4-isopropyl-piperazin-1-yl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile.
申请公布号 NZ597477(A) 申请公布日期 2014.03.28
申请号 NZ20100597477 申请日期 2010.06.09
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 SAKAMOTO HIROSHI;PARK MINJEONG;ITO TOSHIYA;MORIKAMI KENJI;ISHII NOBUYA;KAWADA HATSUO;FURUICHI NORIYUKI;OIKAWA NOBUHIRO;KINOSHITA KAZUTOMO;ASOH KOHSUKE;ONO YOSHIYUKI;KATO YASUHARU;HONG WOOSANG;EMURA TAKASHI
分类号 C07D209/88;A61K31/343;A61K31/381;A61K31/403;A61K31/404;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/5377;A61P25/24;A61P25/28;A61P35/00;A61P35/02;A61P35/04;A61P43/00;C07D307/92;C07D333/76;C07D401/04;C07D401/06;C07D403/04;C07D405/12;C07D405/14;C07D471/04;C07D491/107 主分类号 C07D209/88
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