| 发明名称 |
INHIBITION OF INFLAMMATION USING α7 RECEPTOR-BINDING CHOLINERGIC AGONIST |
| 摘要 |
PROBLEM TO BE SOLVED: To provide treatment of various conditions, using a cholinergic agonist selective for an α7 nicotinic receptor.SOLUTION: A pharmaceutical composition includes a cholinergic agonist having a predetermined structure selective for an α7 nicotinic receptor in an amount sufficient to decrease the amount of proinflammatory cytokines released from macrophages in order to treat colitis. |
| 申请公布号 |
JP2014055178(A) |
申请公布日期 |
2014.03.27 |
| 申请号 |
JP20130257181 |
申请日期 |
2013.12.12 |
| 申请人 |
NORTH SHORE-LONG ISLAND JEWISH RESEARCH INST |
发明人 |
TRACEY KEVIN J;WANG HONG |
| 分类号 |
A61K31/439;A61K31/00;A61K31/444;A61K31/46;A61P1/00;A61P1/04;A61P9/00;A61P11/00;A61P15/00;A61P29/00;A61P31/00;A61P33/00;A61P37/00;A61P43/00;C12N15/09;C12N15/113;C12Q1/68;G01N33/68;G01N33/94 |
主分类号 |
A61K31/439 |
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