发明名称 |
COMPOSITIONS FOR TREATING POSTURAL REFLEX ABNORMALITY CAUSED BY PARKINSON'S DISEASE |
摘要 |
The present disclosure relates to a more effective therapeutic agent capable of improving and treating the axial symptoms (particularly freezing of gait symptom) of patients with Parkinson's disease. Such symptoms in patients with Parkinson's disease can be improved and treated by using L-threo-3,4-dihydroxy-phenylserine (DOPS) and a COMT inhibitor in combination together, optionally with an L-DOPA preparation as well. As a result, the axial symptoms difficult to improve with conventional L-DOPA preparations can be treated, and a therapeutic agent and a treatment method are provided for the axial symptoms of patients with Parkinson's disease, particularly those suffering from the disease at a moderate level or higher. |
申请公布号 |
EP2709608(A1) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20120722056 |
申请日期 |
2012.05.14 |
申请人 |
CHELSEA THERAPEUTICS INC. |
发明人 |
FUKADA, KEI;SAKODA, SABURO |
分类号 |
A61K31/122;A61K31/198;A61K31/275 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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