| 摘要 |
The present invention relates to novel uses of TonEBP gene and more specifically, to a composition for diagnosing eating disorder including a probe or a primer having a complimentary nucleotide sequence of the TonEBP gene, to a kit, and to a microarray. In addition, the present invention relates to a composition for preventing or treating eating disorder which includes an inhibitor which suppresses expression of the gene or suppresses the activities of proteins expressed from the genes and to a method for screening the inhibitor. Especially, the amount of expression increased of the TonEBP protein and the amount of increase or activities of the TonEBP protein suppress appetite; are relate to eating behaviors such as weight reduction and the likes; and can control appetite through at least one among binding of regulators of the TonEBP and the TonEBP so that the TonEBP protein can be utilized as a target gene to diagnose or treat eating disorder; especially obesity, bulimia nervosa, anorexia nervosa, bulimia or cachexia. |
