TRANSVENOUS RENAL NERVE MODULATION FOR TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISORDERS, AND CHRONIC RENAL DISEASES

摘要

A transvenous renal nerve modulation system comprises: a blood pressure monitoring device to be implanted in a patient to monitor the patient's blood pressure; one or more transvenous renal nerve modulation leads to be implanted in one or more renal blood vessels of the patient; a pulse generator coupled to the transvenous renal nerve modulation leads to deliver electrical pulses to the one or more transvenous renal nerve modulation leads for modulating renal nerves of the patient; and a control unit coupled to the blood pressure monitoring device and the pulse generator to control delivery of the electrical pulses by the pulse generator based on the patient's blood pressure from the blood pressure monitoring device. The pulse generator delivers high frequency pulses of greater than about 10 Hz to the transvenous renal nerve modulation leads if the patient's blood pressure is greater than a high blood pressure threshold.