发明名称 AMINO ACID SEQUENCE PRESENTING FUSION POLYPEPTIDE AND ITS USE
摘要 Herein is reported a fusion polypeptide according to formula (I): NH2—S2—X1—S1—COOH, wherein X1 comprises either a random amino acid sequence or an amino acid sequence derived from a first polypeptide, S2 and S1 are non-overlapping amino acid sequences derived from a second polypeptide, and denotes a peptide bond, wherein the second polypeptide is a polypeptide with peptidyl-prolyl cis/trans-isomerase activity (PPIase activity) or is derived from the FKBP-fold domain family, wherein X1 is inserted in place of the insert-in-flap-domain of the second polypeptide.
申请公布号 EP2705147(A1) 申请公布日期 2014.03.12
申请号 EP20120720476 申请日期 2012.05.04
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ANDRES, HERBERT;CASAGOLDA VALLRIBERA, DAVID;DUEFEL, HARTMUT;GERG, MICHAEL;SCHOLZ, CHRISTIAN;SCHRAEML, MICHAEL
分类号 C12N9/90;C07K14/195;C07K14/415;C07K14/47;C07K16/22 主分类号 C12N9/90
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