KERATINOCYTE-ADAPTED MELANOBLAST AND METHOD FOR PRODUCING KERATINOCYTE-ADAPTED MELANOBLAST

摘要

Novel melanoblast is disclosed in the present invention. A production method of the novel melanoblast is also disclosed in the present invention. Specifically, the present invention provides the novel melanoblast which has different gene expression, melanin content, tyrosinase activity, and protein expression compare to existing melanocyte. The present invention also provides the production method of the novel melanoblast for producing melanoblast from the culturing of keratinocyte. [Reference numerals] (AA) After the separation of cultured epithelial cells; (BB) In a PMA- medium; (CC) In a PMA+ medium