The present invention relates to B-domain truncated Factor VIII molecules with a modified circulatory half life, said molecule being covalently conjugated with a hydrophilic polymer. The invention furthermore relates to methods for obtaining such molecules as well as use of such molecules.
申请公布号
AU2009219232(B2)
申请公布日期
2014.02.27
申请号
AU20090219232
申请日期
2009.02.26
申请人
NOVO NORDISK A/S
发明人
DEFREES, SHAWN;BOLT, GERT;VANDAHL, BRIAN BERG STIDSEN;THIM, LARS;STENNICKE, HENNING RALF;STEENSTRUP, THOMAS DOCK
