| 摘要 |
PROBLEM TO BE SOLVED: To provide an agent for preventing and improving skin wrinkle formation having an effect to prevent and improve skin wrinkle formation due to ultraviolet, and an agent for promoting wound healing of the skin.SOLUTION: By using bryonolic acid or its salt, or bryonolic acid dicarboxylic acid ester or its salt, production of type III collagen in dermal fibroblasts can be promoted, skin wrinkle formation can be prevented and improved, and skin wound healing can be promoted. This invention can be used for a medicine, a quasi drug, a cosmetic and the like. |
