发明名称 |
MODIFIED MAREK'S DISEASE VIRUS, AND VACCINES MADE THEREFROM |
摘要 |
The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent. |
申请公布号 |
WO2013142377(A3) |
申请公布日期 |
2014.01.23 |
申请号 |
WO2013US32539 |
申请日期 |
2013.03.15 |
申请人 |
MERIAL LIMITED |
发明人 |
PRITCHARD, JOYCE;MEBATSION, TESHOME;BUBLOT, MICHEL |
分类号 |
A61K39/255;A61P31/22 |
主分类号 |
A61K39/255 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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