发明名称 |
METHOD FOR INDUCING IMMUNE STIMULATION USING NON-PROLIFERATIVE ALLOGENEIC LEUKOCYTES |
摘要 |
This invention relates to cellular-based therapies for decreasing the level of regulatory T cells (Treg) and/or increasing the level of pro-inflammatory T cells (Th17) to favor immune stimulation. To provide these therapeutic effects, a non-proliferative allogeneic leukocyte population is contacted with another leukocyte population capable of proliferating. The leukocyte populations are contacted so as to allow pro-inflammatory allo-recognition. Cellular-based preparations and processes for achieving cellular therapy are also provided. |
申请公布号 |
CA2878610(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
CA20132878610 |
申请日期 |
2013.07.12 |
申请人 |
CANADIAN BLOOD SERVICES |
发明人 |
SCOTT, MARK D.;TOYOFUKU, WENDY M.;WANG, DUNCHENG |
分类号 |
A61K35/14;A61K47/30;A61P37/02;C12N5/078;C12N5/0783 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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