发明名称 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS
摘要 The present invention relates to the method for the treatment of cancer in a subject comprising administering to the subject in need thereof, a therapeutically effective amount of a rho GTPase inhibitor selected from a compound of formula (I) or a compound of formula (II), wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification, in all their stereoisomeric or tautomeric forms, and mixtures thereof in all ratios and their pharmaceutically acceptable salts thereof. The present invention also relates to pharmaceutical compositions comprising a rho GTPase inhibitor selected from one or more compounds of formula (I) or compounds of formula (II) for use in the treatment of cancer.
申请公布号 WO2014009891(A1) 申请公布日期 2014.01.16
申请号 WO2013IB55656 申请日期 2013.07.10
申请人 PIRAMAL ENTERPRISES LIMITED 发明人 NAIK, NISHIGANDHA RAMCHANDRA;CHIMOTE, GEETANJALI CHANDRASHEKHAR
分类号 C07D487/04;A61K31/47;A61K31/519;A61P35/00;C07D215/26 主分类号 C07D487/04
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