发明名称 |
Medium composition comprising neuropeptide Y for the generation, maintenance, prolonged undifferentiated growth of pluripotent stem cells and method of culturing pluripotent stem cell using the same |
摘要 |
The present invention relates to a medium composition comprising neuropeptide Y, effective for proliferation and maintenance of undifferentiated pluripotent stem cells, and a method for culturing undifferentiated pluripotent stem cells using the same. The present invention improves the culture conditions for undifferentiated pluripotent stem cells, and ultimately, the present invention can be effectively used for the development of large-scale culture systems, thereby acquiring clinically applicable pluripotent stem cells. Further, the present invention relates to a dedifferentiation medium composition comprising neuropeptide Y (NPY), and a method for inducing dedifferentiation (or reprogramming) using the same. The present invention improves the culture conditions for dedifferentiation and contributes to develop technology of producing clinically applicable induced pluripotent stem cells, thereby being used for the development of stem cell therapy. |
申请公布号 |
US8628963(B2) |
申请公布日期 |
2014.01.14 |
申请号 |
US201013378912 |
申请日期 |
2010.06.16 |
申请人 |
CHO YEE SOOK;SON MI-YOUNG;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
CHO YEE SOOK;SON MI-YOUNG |
分类号 |
C12N5/00;C12N5/02;C12N5/071 |
主分类号 |
C12N5/00 |
代理机构 |
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地址 |
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