发明名称 |
SOLUTION PREPARATION CONTAINING ANTIBODY AT HIGH CONCENTRATION |
摘要 |
The invention relates to a stable solution preparation containing an antibody, which is characterized by containing arginine and methionine, is provided as a stable antibody-containing preparation suitable for subcutaneous administration wherein dimer formation and deamidation are prevented during prolonged storage. |
申请公布号 |
UA104134(C2) |
申请公布日期 |
2014.01.10 |
申请号 |
UA20100009396 |
申请日期 |
2008.12.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG |
发明人 |
MORICHIKA, TOSHIYUKI;KAMEOKA, DAISUKE;IMAEDA, YOSHIMI;MAEDA, TERUTOSHI;STAUCH, OLIVER BORIS |
分类号 |
A61K39/395;A61K9/08;A61K47/18 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|