| 摘要 |
The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates alphaCD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon alphaCD3/alphaGITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed |
