| 发明名称 |
Method for treating ocular cancer |
| 摘要 |
It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53 activator. In particular embodiments, the p53 activator blocks the interaction between DM2 or DMX and p53. As the p53 activator induces ocular cancer cell death, a method for preventing or treating ocular cancer is also provided. |
| 申请公布号 |
US8614192(B2) |
申请公布日期 |
2013.12.24 |
| 申请号 |
US20070373308 |
申请日期 |
2007.07.24 |
| 申请人 |
DYER MICHAEL A.;MARINE JEAN-CHRISTOPHE;JOCHEMSEN AART GERRIT;LEIDEN UNIVERSITY MEDICAL CENTER;FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY, VIB;ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
DYER MICHAEL A.;MARINE JEAN-CHRISTOPHE;JOCHEMSEN AART GERRIT |
| 分类号 |
A01N61/00;A61K31/00;A61K38/00 |
主分类号 |
A01N61/00 |
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