ANTI-ANGIOGENIC COMPOSITION CONTAINING MACROLACTIN A AND A DERIVATIVE THEREOF AS ACTIVE INGREDIENTS

摘要

The present invention relates to an anti-angiogenic composition containing macrolactin compounds such as macrolactin A, 7- O -malonyl macrolactin A, and 7- O- succinyl macrolactin A as active ingredients. The macrolactin compounds according to the present invention strongly suppress angiogenesis in in vivo experiments and can be used as a pharmaceutical composition for preventing or treating diseases caused by angiogenesis.