| 摘要 |
The invention is related to determining the expression status of the human epidermal growth factor receptor 2 (HER2), diagnosing cancer and predicting the response of a cancer patient to a drug or predicting the prognosis of a cancer patient. The method according to the invention comprises measuring amounts of two or more proteins in a sample, wherein the two or more proteins have substantially one of following molecular weights 4740, 8404, 8419, 8435, 8450, 8455, 8465, 8570, 8607 or 8626 atomic mass units, or measuring amounts of at least one of the human cystein-rich intestinal protein 1 (CRIP1), one or more variants of the human cystein-rich intestinal protein 1 (CRIP1 variants), and of proteolytic digestion products thereof in the sample. |
