A method for quantifying peaks in an analytical signal

摘要

In a computer, a method for quantifying peaks in an analytical signal Peaks in an analytical signal are quantified by recording successive signal values and applying a peak analysis algorithm to the signal values within an interval for obtaining a set of peak quantification results. To facilitate optimizing the parameters of the peak analysis algorithm and to improve the robustness of the method in runtime applications, random noise is added to the analytical signal and/or the signal is shifted within the interval, before the same peak analysis algorithm is applied to the modified signal to quantify the peaks in the signal. The step sequence of noise addition and/or signal shift and peak quantification may be repeated multiple times with different noise and/or different amount and/or direction of shift added or applied to the originally recorded signal each time. The noise-addition technique and signal-shift technique can be used either alone or together as needed. A subsequent statistical evaluation of the peak quantification results from the multiple repeated peak analyses of the original and modified signals is used to detect an occurrence of and to reduce the chance of a possible error in the peak quantification that needs to be alarmed or addressed.