发明名称 |
NOVOBIOCIN ANALOGUES AS ANTICANCER AGENTS |
摘要 |
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents. |
申请公布号 |
EP1807440(A4) |
申请公布日期 |
2013.12.11 |
申请号 |
EP20050824355 |
申请日期 |
2005.11.03 |
申请人 |
THE UNIVERSITY OF KANSAS;DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
BLAGG, BRIAN, S.;NECKERS, LEN;YU, XIAO, MING |
分类号 |
C07H17/075;A61K31/7048;A61P25/00;A61P35/00 |
主分类号 |
C07H17/075 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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