发明名称 NOVEL beta-LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME
摘要 Currently available beta-lactamase inhibitors have an inadequate effect against beta-lactamases, which continue to increase constantly. There is a need for novel beta-lactamase inhibitors which can be used in the treatment of bacterial infections caused by resistant bacteria that are currently difficult to treat and that produce: class C beta-lactamase; extended-spectrum beta-lactamase (ESBL) belonging to classes A and D; KPC-2, which decomposes even carbapenem, the last bastion of beta-lactam antibiotics, belonging to class A; and the like. Provided are a compound shown by formula (I), a method for producing the same, a beta-lactamase inhibitor, and a method for treating bacterial infections.
申请公布号 WO2013180197(A1) 申请公布日期 2013.12.05
申请号 WO2013JP64971 申请日期 2013.05.30
申请人 MEIJI SEIKA PHARMA CO., LTD. 发明人 ABE, TAKAO;FURUUCHI, TAKESHI;SAKAMAKI, YOSHIAKI;INAMURA, SEIICHI;MORINAKA, AKIHIRO
分类号 C07D471/08;A61K31/439;A61K31/444;A61K31/4545;A61K31/5377;A61P31/04;A61P43/00;C07D211/60 主分类号 C07D471/08
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