FUSION PROTEINS COMPRISING CD4 MINIMAL MODULES AND METHODS OF USE THEREOF
摘要
Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.
申请公布号
CA2569562(C)
申请公布日期
2013.12.03
申请号
CA20052569562
申请日期
2005.06.08
申请人
CHIRON CORPORATION
发明人
MASIGNANI, VEGA;SCARSELLI, MARIA;CAPECCHI, BARBARA;SHARMA, VICTORIA;BARNETT, SUSAN W.;SRIVASTAVA, INDRESH K.;RAPPUOLI, RINO