| 发明名称 |
Pyrazolo[1,5-a]pyrimidine derivatives as mTOR inhibitors |
| 摘要 |
The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.
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| 申请公布号 |
US8591943(B2) |
申请公布日期 |
2013.11.26 |
| 申请号 |
US201013263193 |
申请日期 |
2010.04.08 |
| 申请人 |
DENG YONGQI;SUN BINYUAN;ZENG HONGBO;RICHARDS MATTHEW;SHIPPS, JR. GERALD W.;CHENG CLIFF C.;ZHAO YINYAN;MCRINER ANDREW;MENG ZHAOYANG;NAN YANG;PATEL MEHUL F.;WRONA IWONA E.;REDDY PANDURANGA ADULLA;EKLOV BRIAN M.;TANG SHUYI;LIU DUAN;MANDAL AMIT K.;ZHAO LIANYUN;SIDDIQUI M. ARSHAD;MERCK SHARP & DOHME CORP. |
发明人 |
DENG YONGQI;SUN BINYUAN;ZENG HONGBO;RICHARDS MATTHEW;SHIPPS, JR. GERALD W.;CHENG CLIFF C.;ZHAO YINYAN;MCRINER ANDREW;MENG ZHAOYANG;NAN YANG;PATEL MEHUL F.;WRONA IWONA E.;REDDY PANDURANGA ADULLA;EKLOV BRIAN M.;TANG SHUYI;LIU DUAN;MANDAL AMIT K.;ZHAO LIANYUN;SIDDIQUI M. ARSHAD |
| 分类号 |
A61K9/127;A61K31/519;A61K31/5377;A61K31/538;A61K31/541;A61K31/551;A61K31/553;A61K31/554;A61K31/704;A61K33/24;A61K38/50;A61K39/395 |
主分类号 |
A61K9/127 |
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