发明名称 |
NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS |
摘要 |
Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. |
申请公布号 |
KR20130128460(A) |
申请公布日期 |
2013.11.26 |
申请号 |
KR20137024772 |
申请日期 |
2012.02.23 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
ANAND RAJAN;APGAR JAMES M.;BIFTU TESFAYE;CHEN PING;CHU LIN;COLANDREA VINCENT J.;DONG GUIZHEN;DROPINSKI JAMES F.;FENG DANQING;HICKS JACQUELINE D.;JIANG JINLONG;KIM ALEXANDER J.;LEAVITT KENNETH J.;LI BING;QIAN XIAOXIA;SEBHAT IYASSU;WEI LAN;WILKENING ROBERT R.;WU ZHICAI |
分类号 |
C07D471/04;A61K31/437;A61P3/10;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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