发明名称 |
FORMATION OF NEUROMUSCULAR JUNCTIONS IN A DEFINED SYSTEM |
摘要 |
A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more human muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a human muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions. |
申请公布号 |
EP2585171(A4) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20110772857 |
申请日期 |
2011.05.06 |
申请人 |
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
HICKMAN, JAMES;GUO, XIUFANG |
分类号 |
A61P21/00;C12N5/077;C12N5/079 |
主分类号 |
A61P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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