发明名称 |
18-membered macrocycles and analogs thereof |
摘要 |
The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. In particular, this compound is a potent drug for the treatment of bacterial infections, specifically C. difficile infections.
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申请公布号 |
US8586551(B2) |
申请公布日期 |
2013.11.19 |
申请号 |
US20090551056 |
申请日期 |
2009.08.31 |
申请人 |
SHUE YOUE-KONG;HWANG CHAN-KOU;CHIU YU-HUNG;ROMERO ALEX;BABAKHANI FARAH;SEARS PAMELA;OKUMU FRANKLIN;OPTIMER PHARMACEUTICALS, INC. |
发明人 |
SHUE YOUE-KONG;HWANG CHAN-KOU;CHIU YU-HUNG;ROMERO ALEX;BABAKHANI FARAH;SEARS PAMELA;OKUMU FRANKLIN |
分类号 |
A01N43/04;A61K31/70;C07G3/00;C07H1/00 |
主分类号 |
A01N43/04 |
代理机构 |
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