| 发明名称 |
SINGLE DOMAIN BINDING MOLECULE |
| 摘要 |
The present invention provides a single domain specific binding molecule having the structure5 FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino10 acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain. |
| 申请公布号 |
WO2013167883(A1) |
申请公布日期 |
2013.11.14 |
| 申请号 |
WO2013GB51183 |
申请日期 |
2013.05.07 |
| 申请人 |
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN |
发明人 |
BARELLE, CAROLINE;MUELLER, MISCHA;CALABRO, VALERIE;BIKKER, JACK A;STEVEN, JOHN;TCHISTIAKOVA, LIOUDMILA;KOVALENKO, OLEG;OLLAND, ANDREA |
| 分类号 |
C07K16/44 |
主分类号 |
C07K16/44 |
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