发明名称 |
SEPARATION OF CONTAMINANTS FROM STREPTOCOCCUS PNEUMONIAE POLYSACCHARIDE BY PH MANIPULATION |
摘要 |
A process for reducing the protein content and preserving the capsular polysaccharide content in a complex cellular Streptococcus pneumoniae lysate broth prior to purification is described. Utilizing pH reduction after cellular lysis has resulted in a purified polysaccharide that consistently meets the protein specification, and higher recovery yields of polysaccharide during the purification process.
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申请公布号 |
CA2604362(C) |
申请公布日期 |
2013.11.12 |
申请号 |
CA20062604362 |
申请日期 |
2006.03.31 |
申请人 |
WYETH |
发明人 |
BAHLER, BRIAN;LEE, TSU-SHUN;LOTVIN, JASON ARNOLD;RUPPEN, MARK EDWARD;CHARBONNEAU, PAMELA SUE FINK |
分类号 |
C08B37/00;A61K39/09 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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