发明名称 |
Benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof |
摘要 |
The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
|
申请公布号 |
US8580848(B2) |
申请公布日期 |
2013.11.12 |
申请号 |
US201213489261 |
申请日期 |
2012.06.05 |
申请人 |
KANG DONG WOOK;LEE JEE WOO;KIM YOUNG HO;KIM HEE;HA HEE JIN;NAM EUN JOO;JOUNG CHAN MI;DAEWOONG PHARMACEUTICAL CO., LTD.;MEDIFRON DBT CO., LTD. |
发明人 |
KANG DONG WOOK;LEE JEE WOO;KIM YOUNG HO;KIM HEE;HA HEE JIN;NAM EUN JOO;JOUNG CHAN MI |
分类号 |
A61K31/34;C07D307/00 |
主分类号 |
A61K31/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|