摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for external application and an adhesive skin patch capable of improving releasability, transdermal absorbability and stability of loxoprofen and a salt thereof and capable of reducing aggravation of irritation to skin.SOLUTION: An adhesive skin patch includes a support and an adhesive layer laminated on the support. The adhesive layer includes a styrene-isoprene-styrene copolymer, a tackifier, a plasticizer, sodium loxoprofen, oxyacid and N-methyl-2-pyrrolidone. Preferably, the adhesive layer includes no crotamiton. |