发明名称 |
DETERMINATION OF TOTAL ANALYTE CONCENTRATION |
摘要 |
Methods and reagents are disclosed for determining a total amount of an analyte in an unknown sample suspected of containing the analyte in the presence of endogeneous interfering substances. The methods involve measuring an amount [Y] of the portion of the analyte in the unknown sample that is bound by endogeneous binding substances employing an assay for the analyte. An amount [Z] of analyte in the unknown sample that is not bound by endogeneous binding substances is determined by the formula: [Z]=a[Y]+b, wherein "a" and "b" are predetermined by conducting the assay on samples containing known amounts of the analyte but substantially free from endogeneous interfering substances. Adding [Y] and [Z] yields the total amount [X] of the analyte in the unknown sample. |
申请公布号 |
US2013295592(A1) |
申请公布日期 |
2013.11.07 |
申请号 |
US201213465574 |
申请日期 |
2012.05.07 |
申请人 |
WEI TIE QUAN;SIEMENS HEALTHCARE DIAGNOSTICES INC. |
发明人 |
WEI TIE QUAN |
分类号 |
G01N21/76;G01N21/64;G01N33/53;G06F19/00 |
主分类号 |
G01N21/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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