发明名称 |
PROCESS FOR PRODUCTION OF HEMATOPOIETIC STEM CELL |
摘要 |
An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided. A method of producing hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises expanding hematopoietic stem cells by culturing hematopoietic stem cells ex vivo in the presence of a compound represented by the formula following (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof (wherein R 1 to R 6 are as defined in the description). |
申请公布号 |
EP2581442(A4) |
申请公布日期 |
2013.11.06 |
申请号 |
EP20110795711 |
申请日期 |
2011.06.13 |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD.;NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY |
发明人 |
NISHINO, TAITO;IWAMA, ATSUSHI |
分类号 |
A61K31/122;A61K31/352;C12N5/0789 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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