发明名称 |
GLUCAGON RECEPTOR MODULATORS |
摘要 |
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon. |
申请公布号 |
EP2655331(A1) |
申请公布日期 |
2013.10.30 |
申请号 |
EP20110805952 |
申请日期 |
2011.12.09 |
申请人 |
PFIZER INC. |
发明人 |
ASPNES, GARY, ERIK;DIDIUK, MARY, THERESA;FILIPSKI, KEVIN, JAMES;GUZMAN-PEREZ, ANGEL;PFEFFERKORN, JEFFREY, ALLEN;STEVENS, BENJAMIN, DAWSON;TU, MEIHUA, MIKE |
分类号 |
C07D213/82;A61K31/44;A61K31/4427;A61K31/4965;A61K31/505;A61P3/10;C07D239/42;C07D241/28;C07D401/12;C07D403/12;C07D405/12 |
主分类号 |
C07D213/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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