The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present invention have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention compositions include an anhydrous crystal form of adefovir dipivoxil.
申请公布号
HK1091211(A1)
申请公布日期
2013.10.11
申请号
HK20060111839
申请日期
2006.10.26
申请人
GILEAD SCIENCES INC.
发明人
ARIMILLI, MURTY, N.;LEE, THOMAS, T., K.;MANES, LAWRENCE, V.;PRISBE, ERNEST, J.;SCHULTZE, LISA, M.;KELLY, DAPHNE, E.;MUNGER, JOHN, D., JR.