METHODS OF TREATING GLUCOSE METABOLISM DISORDERS

摘要

Methods of treating individuals with a glucose metabolism disorder, and compositions suitable for use in the methods, are provided. As described in the disclosure, peptide subsequences derived from the Tor2a gene product have been identified. More particularly, ten murine peptides (ms p1-ms p10) and ten human peptides (hu p1-hu p10) have been identified (see Figure 2), and these peptides are distinct from the salusin peptides (i.e., neither the murine peptides nor the human peptides overlap with the murine and human amino acid sequences of the salusin peptides.