发明名称 |
PROCEDE DE LIGATION NATIVE DE POLYPEPTIDES |
摘要 |
<p>The invention mainly relates to a method for manufacturing a polypeptide of formula: X1—X″—X2 (III) X1 and X2 each representing a peptide fragment, and X″representing an amino acid residue comprising a thiol function, said method comprising at least one step of ligation reaction between a polypeptide of formula: X1—N(CH2CH2SH)2 (I) and a polypeptide of formula: H—X″—X2. (II) The invention also relates to the polypeptides of formula (I) themselves and the method for obtaining them, as well as resin supports suitable for obtaining them.</p> |
申请公布号 |
FR2952058(B1) |
申请公布日期 |
2013.10.04 |
申请号 |
FR20090057639 |
申请日期 |
2009.10.29 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT PASTEUR DE LILLE |
发明人 |
MHIDIA REDA;DHEUR JULIEN;OLLIVIER NATHALIE;MELNYK OLEG |
分类号 |
C07K1/02;C07C323/29;C07K1/04;C07K1/107;C07K2/00;C07K7/64;C07K17/06 |
主分类号 |
C07K1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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