Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors

摘要

C:NRPnbhDCORXS/4502194_1 DOC-30/07/2012 The present invention provides substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical compositions containing those compounds which can be used in methods of treating, inhibiting the growth of or eradicating a neoplasm in a mammal. The compounds and pharmaceutical compositions containing them may also be used on methods of treating, inhibiting the progression of or eradicating polycystic kidney disease in a mammal. The present invention also provides a process for preparing the compounds of this invention.